Description

ABSTRACT

Özkan R, Kaya B, Kaya G. Vascular occlusion following hyaluronic acid injection: A case report.

Undersea Hyperb Med. 2026 First Quarter; 53(1):47-50.

Introduction: This case presentation discusses vascular occlusion following hyaluronic acid (HA) injection

and the subsequent treatment.

Case Report: A 52-year-old female underwent a 0.2 ml HA filler injection for aesthetic purposes in

the forehead area, followed by the development of discoloration and severe pain extending from the

glabellar region to the forehead.

Discussion: The diagnosis was determined as vascular occlusion due to the injection, and the patient

received 300 IU of hyaluronidase immediately. Additionally, hyperbaric oxygen treatment (HBO2) was

initiated. The patient received seven HBO2 treatments and healed without developing post-treatment

necrosis. No scar formation was observed at the three-month follow-up. This case highlights the potential

benefits of HBO2 in managing complications arising from HA fillers. It underscores the importance of

physicians performing aesthetic procedures, being attentive to facial anatomy and injection techniques

to prevent such complications. Furthermore, having knowledge about the effectiveness of HBO2

in potential complication scenarios and collaboration with hyperbaric clinics when necessary are

recommended.

Keywords: Filler complications; hyaluronidase hyperbaric oxygen treatment; hyaluronic acid; intra-arterial injection

DOI: 10.22462/838