Description

ABSTRACT

Singh S, Nevarez J. Hyperbaric Oxygen Treatment for Arterial Gas Embolism With Transient Cortical

Blindness Following Intravenous Ozone Therapy: A Case Report. Undersea Hyperb Med. 2026

Second Quarter; 53(2):243-246.

Introduction: Cerebral arterial gas embolism (CAGE) is a rare but potentially fatal condition that can

occur when air enters the arterial circulation.

Case Report: This case report describes a 64-year-old female patient who experienced a sudden onset of

left lower extremity weakness and bilateral vision loss following a session of intravenous ozone therapy.

Initial diagnostic imaging did not reveal any acute abnormalities. However, her clinical presentation was

consistent with CAGE. She was initially administered emergent hyperbaric oxygen (HBO2) at 2.8 ATA,

followed by additional sessions at 2.0 ATA, which led to progressive symptomatic improvement and full

resolution of her visual and motor deficits.

Discussion: This case highlights the importance of recognizing the potential complications of

intravenous ozone therapy, including CAGE. Hyperbaric oxygen treatment should be considered an

option for patients with AGE following this procedure.

Keywords: air embolism; arterial gas embolism; case reports; hyperbaric oxygen treatment; intravenous

ozone; vision